Two things Luigi's Mansion 2 and a new Donkey Kong.
I've said about my idea for Luigi's Mansion before, have it as a sequel and luigi is running some kind of ghostbusters esque firm. would open the way for all kinda of locations, you could use the remote as the torch, and the maybe the nunchuck for the vacuum, how about hold down its trigger and spin the nunchuck to suck up ghosts?
donkey kong, just wanna see a new platformer, more like dkc tho that dk64, maybe you could use the tilt sensors in the wiimote and nunchuck to control each of donkey kongs arms when swinging on vines? could also work for combat system aswell?