The whole idea behind his science skill is that he's a genius. Not smart,but an actual genius, potentially wasting his potential as Spider-Man. He should have gone on to found bio-tech think tanks or something but as it is, Peter parker can barely hold down a part time job.
I always liked that in Ultimate spider-man, Ben tells him the power and resposibility line in relation to doing his homework because he can, and should, use his inteligence to help the world. it just doesn't end that way.