I think it could potentially work with RTS gamers like myself who prefer to just methodically play the game, build up and army at a slow pace but say a game like Starcraft 2 would run so fast that I just couldnt see them ever wanting to look away at a tablet screen. Plus keyboard and mouse on consoles never seems to work that well if you are sitting on a sofa for example (which I would assume a lot of console gamers would be).
As for if the Wii U actually supports keyboard & mouse, I'm not sure. Just trying to think of any games that might be able to use it.