L.A. Noire is a third-person, post-war murder mystery set in 1947 Los Angeles. It is being developed by Team Bondi, an Australian studio, and is being published by Rockstar Games. Although it is fully funded by Sony Computer Entertainment America, it will be released May 20th 2011 on both the PlayStation 3 and Xbox 360.
The impressive cast includes:
Aaron Staton (Mad Men)
Alexa Alemanni (Mad Men)
William Duffy (The West Win)
John Noble (The Lord of the Rings, Fringe)
Keith Szarabajka (The Dark Knight)
Ned Vaughn (Apollo 13, Frost/Nixon)
This features the best facial animation I've ever seen, as seen in their "technology behind performance" video (the short John Noble opener blew me away). That video (must see) and the trailers can be seen here.
Edit: Here's the same video on YouTube