I'm lazy and copying this from a different forum post, so I address some issues that another user had, while they are relevant, the context may seem a little weird without the other post. That said here is my long impressions plus pics.
Well, first and foremost I'll address NBTs complaints.
In my 10 hours of playing Fallout 3 I have encountered 4 glitches. One of which I'm not positive of. I've clipped into a wall once, and all I had to do was leave through the edge (the edge being the end of the wall). Another was when the ground texture didn't load in at a seam in the world (I have a pic for this one). The third definant glitch happened in Megaton. I walked out of a building and saw straight across from me a body falling off a ledge then land dead at the ground. I'm certain she died before the fall because the radgoll physics were in effect (and going whack). The last one is the most odd. Instead of being evil and blowing Megaton up, I decided to turn the guy in, so I went and talked to the sheriff. The sheriff(Simms) and I went to go arrest the culprit, we go to the saloon and after a bit of talking the guy decides to go peacefully, but as Simms turns away he pulls a gun and kills him. Naturally I reloaded to try and save Simms, well I got the drop on the enemy and attacked before he could shoot Simms (which broke his AI btw) as this happened Simms ran away like a little girl. After the fight, I went to try and find Simms......well I did, but he was dead at the bottom of a hill. My guess is that saving him somehow may break the scripting and thus isn't possible.
Now that were through with that.
The pip-boy, imo is worse than Oblivion's UI, at first at least. It took me a little bit but I am use to the Pip-boy and it isn't too bad, but navigating it is still a little odd, my mouse lags while using the PB. There is no hotkeying weapons (at least on PC...) so until you get use to the PB switching weapons (and you'll do it often at first) is a bit of a pain. For me VATS works great, except it suffers from the same mouse lag as the PB and selecting different body parts also lags.
At first I found combat without using VATS hard to do (may be poor preformance on my laptops part) but I'm more accustomed to the ins and outs and can generally kill things out of VATS. The 3rd person view is over the shoulder and many times much better than any 3rd person attemped in TES games. Melee combat works well and can be effective (got a pic for that too) but while in Melee VATS only allows a attack at the enemy, instead of specific parts. As far as levels and enemy power (in response to NBT) no Molerat should have survived a well place grenade, I was beating them to death with a baseball bat at level 2.
Skills and perks....well they kept plenty of things intact from the old games yet changed them to reflect the changes in gaming. Every skill is useful to have, although depending on your playstyle there are more useful skills to have. I'm not sure what else to write on this subject.
Exploration.....is wonderful, it all feels much more varied from Oblivion where one dungeon was interchangable with nearly any other dungeon. Out in the wastes it feels unique, and so far it seems that places to explore are less in numbers than TES, but I think that may be since the overworld it's self is like a large varied Dungeon you could take an uneventful stroll through a ruined town, or you may step into a town and sniper fire could rain down apon you.
As to the differences in experience between NBT and I, it may be *shudder* platform differences. As I was playing so was A Reaver, and we were confering as we played, and near as I can tell we both had enjoyable experiences with nary a game breaking bug.
now for pics...
These are all just straight up Medium Quality no AA 1280x800(photobucket resized though )
Mother-****ing Fire Breathing ANTS!!!!. They're attacking each other in that pic. ^
One ant killed the other.
This thing scared the **** out of me, I was looking up at a corpse hanging on meat hooks.
Shot him in VATS.
Finished him with my bat.....I was practically out of ammo.
Grenade exploding near some Mirelurks, they have tough armor.
No Texture, for like 10 seconds. I took half a step after the pic though and it appeared.
Spooning Skeletons. el oh el.
Damn sniper blew a car up.
She was sleeping and I shot her head off. I reloaded after that though.
I wish I was quicker on the button for this one, VATS slo-mo followed my bullet until it hit their face and took off the head.
Wow, this took 50 minutes to type.
Ummm yeah, just remembered I forgot AI. Well not too much to say usually it's basic, but downright stupid, people will wait for you to come closer before revealing themselves(occasionally). The best example so far would be a group of 3 Super Mutants, but I only knew of two. Well we had a fire fight (one had a minigun he crippled my head...) I was wandering about looting and exploring still. When I got close to where they were the third popped out from behind a crumbling wall abour 3 feet in front of me and charged with his Melee weapon. I was surprised that he was smart enough to hide until I got close to him as oppose to charging into bullets with a 2x4. Oh and I dropped the Minigun mutant first, and his living buddy ran up and took the minigun to use on me. I've also shot weapons out of raiders hands at which point they will turn around and scramble to re-equip their weapon.