Yeah, was trying to think of something that wouldn't give the game away too easily.
The game was released in 1995, and had an expansion pack released in 1996. Both games carried a subtitle "No ____" and each blank is a synonym for guilt.
Oh and to make it a little easier, here's the box art
[ATTACH]2739[/ATTACH]
Just saw darksnowmans guess of X-Com, which is...wrong.
Another quick clue, it featured FMV with mission briefings and cut scenes. One of the characters has also done voice work for Sonic, Metriod Prime, and stared in the original Texas Chainsaw Massacre.