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Chi019

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  1. 'Science's Last Taboo'

    The problem with the documentary is that they commit the Lewontin fallacy to make their argument. That is that there is greater variation within groups than between them. Cambridge geneticist AWF Edwards debunked this in a 2003 paper. Basically, while it is correct for individual genes, this overlooks the correlations and the fact genes vary in frequency across groups. Armand Leroi explains the fallacy here: "The dominance of the social construct theory can be traced to a 1972 article by Dr. Richard Lewontin, a Harvard geneticist, who wrote that most human genetic variation can be found within any given "race." If one looked at genes rather than faces, he claimed, the difference between an African and a European would be scarcely greater than the difference between any two Europeans. A few years later he wrote that the continued popularity of race as an idea was an "indication of the power of socioeconomically based ideology over the supposed objectivity of knowledge." Most scientists are thoughtful, liberal-minded and socially aware people. It was just what they wanted to hear. Three decades later, it seems that Dr. Lewontin's facts were correct, and have been abundantly confirmed by ever better techniques of detecting genetic variety. His reasoning, however, was wrong. His error was an elementary one, but such was the appeal of his argument that it was only a couple of years ago that a Cambridge University statistician, A. W. F. Edwards, put his finger on it. The error is easily illustrated. If one were asked to judge the ancestry of 100 New Yorkers, one could look at the color of their skin. That would do much to single out the Europeans, but little to distinguish the Senegalese from the Solomon Islanders. The same is true for any other feature of our bodies. The shapes of our eyes, noses and skulls; the color of our eyes and our hair; the heaviness, height and hairiness of our bodies are all, individually, poor guides to ancestry. But this is not true when the features are taken together. Certain skin colors tend to go with certain kinds of eyes, noses, skulls and bodies. When we glance at a stranger's face we use those associations to infer what continent, or even what country, he or his ancestors came from - and we usually get it right. To put it more abstractly, human physical variation is correlated; and correlations contain information. Genetic variants that aren't written on our faces, but that can be detected only in the genome, show similar correlations. It is these correlations that Dr. Lewontin seems to have ignored. In essence, he looked at one gene at a time and failed to see races. But if many - a few hundred - variable genes are considered simultaneously, then it is very easy to do so. Indeed, a 2002 study by scientists at the University of Southern California and Stanford showed that if a sample of people from around the world are sorted by computer into five groups on the basis of genetic similarity, the groups that emerge are native to Europe, East Asia, Africa, America and Australasia - more or less the major races of traditional anthropology. " nytimes.com/2005/03/14/opinion/14leroi.html?pagewanted=2 Steve Hsu also explains this here and that as further genome sequencing becomes available more information on group differences will come to light: "There is no strong evidence yet for specific gene variants (alleles) that lead to group differences (differences between clusters) in behavior or intelligence, but progress on the genomic side of this question will be rapid in coming years, as the price to sequence a genome is dropping at an exponential rate. What seems to be true (from preliminary studies) is that the gene variants that were under strong selection (reached fixation) over the last 10k years are different in different clusters. That is, the way that modern people in each cluster differ, due to natural selection, from their own ancestors 10k years ago is not the same in each cluster -- we have been, at least at the genetic level, experiencing divergent evolution. In fact, recent research suggests that 7% or more of all our genes are mutant versions that replaced earlier variants through natural selection over the last tens of thousands of years. There was little gene flow between continental clusters ("races") during that period, so there is circumstantial evidence for group differences beyond the already established ones (superficial appearance, disease resistance). infoproc.blogspot.com/2008/01/no-scientific-basis-for-race.html "Dec. 10, 2007 - Researchers discovered genetic evidence that human evolution is speeding up - and has not halted or proceeded at a constant rate, as had been thought - indicating that humans on different continents are becoming increasingly different. "We used a new genomic technology to show that humans are evolving rapidly, and that the pace of change has accelerated a lot in the last 40,000 years, especially since the end of the Ice Age roughly 10,000 years ago," says research team leader Henry Harpending, a distinguished professor of anthropology at the University of Utah. Harpending says there are provocative implications from the study, published online Monday, Dec. 10 in the journal Proceedings of the National Academy of Sciences: "We aren't the same as people even 1,000 or 2,000 years ago," he says, which may explain, for example, part of the difference between Viking invaders and their peaceful Swedish descendants. "The dogma has been these are cultural fluctuations, but almost any Temperament trait you look at is under strong genetic influence." "Human races are evolving away from each other," Harpending says. "Genes are evolving fast in Europe, Asia and Africa, but almost all of these are unique to their continent of origin. We are getting less alike, not merging into a single, mixed humanity." He says that is happening because humans dispersed from Africa to other regions 40,000 years ago, "and there has not been much flow of genes between the regions since then." unews.utah.edu/p/?r=120607-1
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